New Books In Medicine

Cancer exists in nearly every animal and has afflicted humans as long as our species has walked the earth. In Rebel Cell: Cancer, Evolution, and the New Science of Life's Oldest Betrayal (Benbella Books, 2020), Kat Arney reveals the secrets of our most formidable medical enemy, most notably the fact that it isn't so much a foreign invader as a double agent: cancer is hardwired into the fundamental processes of life. New evidence shows that this disease is the result of the same evolutionary changes that allowed us to thrive. Evolution helped us outsmart our environment, and it helps cancer outsmart its environment as well—alas, that environment is us. Rebel Cell is a story about life and death, hope and hubris, nature and nurture. It's about a new way of thinking about what this disease really is and the role it plays in human life. Above all, it's a story about where cancer came from, where it's going, and how we can stop it. Matthew Jordan is a professor at McMaster University, where he teaches courses on A

Relationship problems, struggles with substance abuse, poor memory, and difficulties with emotions are typical symptoms of complex trauma—yet many traumatized individuals have no idea their symptoms share a common cause. Research shows that treating one’s underlying traumatic experiences can yield immense relief from such symptoms and liberate individuals to live freer, more satisfying lives. This has been the focus of Dr. Tamara McClintock Greenberg’s work for 30 years, as she documents in her new book, Treating Complex Trauma: Combined Theories and Methods (2020, Springer). In our interview, we tackle such topics as the distinction between trauma and complex trauma, how to treat it, and the intersection of trauma with race and culture. This episode is for anyone who struggles with symptoms and difficulties that elude explanation or those who know someone who does. Tamara McClintock Greenberg, Psy.D., M.S., is a clinical psychologist in private practice in San Francisco, CA, where she specializes in treating

Since the dawn of the industrial age, we have unleashed a bewildering number of potentially harmful chemicals. But out of this vast array, how do we identify the actual threats? What does it take to prove that a certain chemical causes cancer? How do we translate academic knowledge of the toxic effects of particular substances into understanding real-world health consequences? The science that answers these questions is toxicology. In The Alchemy of Disease: How Chemicals and Toxins Cause Cancer and Other Illnesses (Columbia University Press), John Whysner offers an accessible and compelling history of toxicology and its key findings. He details the experiments and discoveries that revealed the causal connections between chemical exposures and diseases. Balancing clear accounts of groundbreaking science with human drama and public-policy relevance, Whysner describes key moments in the development of toxicology and their thorny social and political implications. The book features discussions of toxicological p

In her new book Diabetes: A History of Race and Disease (Yale University Press, 2020), Arleen Tuchman, professor of history at Vanderbilt University, describes the history of how the perception of diabetes has evolved over the past two centuries. She charts the chronology of diabetes, from its beginnings as a disease associated with Jews to one associated with “non-whites.” She explores the connotations that patients, advocates, physicians, and policymakers have attached to diabetes (e.g., disease of the “civilized” versus disease of the “primitive”) and how researchers have consistently missed socioeconomic factors that may represent the most important risk factor for the disease. Alec Kacew is a medical school student at the University of Chicago. Learn more about your ad choices. Visit megaphone.fm/adchoices

Against the backdrop of a post-Soviet state set aflame by geopolitical conflict and violent revolution, Narkomania: Drugs, HIV, and Citizenship in Ukraine (Cornell UP, 2019) considers whether substance use disorders are everywhere the same and whether our responses to drug use presuppose what kind of people those who use drugs really are. Jennifer J. Carroll's ethnography is a story about public health and international efforts to quell the spread of HIV. Carroll focuses on Ukraine where the prevalence of HIV among people who use drugs is higher than in parts of sub-Saharan Africa and unpacks the arguments and myths surrounding medication-assisted treatment (MAT) in Ukraine. What she presents in Narkomania forces us to question drug policy, its uses, and its effects on "normal" citizens. Carroll uses her findings to explore what people who use drugs can teach us about the contemporary societies emerging in post-Soviet space. With examples of how MAT has been politicized, how drug use has been tied to ideas of

In the early twentieth century, public health reformers approached the task of ameliorating unsanitary conditions and preventing epidemic diseases with optimism. Using exhibits, they believed they could make systemic issues visual to masses of people. Embedded within these visual displays were messages about individual action. In some cases, this meant changing hygienic practices. In other situations, this meant taking up action to inform public policy. Reformers and officials hoped that exhibits would energize America's populace to invest in protecting the public's health. Exhibiting Health is an analysis of the logic of the production and the consumption of this technique for popular public health education between 1900 and 1930. It examines the power and limits of using visual displays to support public health initiatives. Jennifer Lisa Koslow is an associate professor of history and director of the Historical Administration and Public History program at Florida State University in Tallahassee. She is the

Policing the Womb: Invisible Women and the Criminalization of Motherhood (Cambridge University Press, 2020) a brilliant but shocking account of the criminalization of all aspects of reproduction, pregnancy, abortion, birth, and motherhood in the United States. In her extensively researched monograph, Michele Goodwin recounts the horrific contemporary situation, which includes, for example, mothers giving birth shackled in leg irons, in solitary confinement, even in prison toilets, and in some states, women being coerced by the State into sterilization, in exchange for reduced sentences. She contextualises the modern day situation in America’s history of slavery and oppression, and also in relation to its place in the world. Goodwin shows how prosecutors abuse laws, and medical professionals are complicit in a system that disproportionally impacts the poor and women of color. However, Goodwin warns that these women are just the canaries in the coalmine. In the context of both the Black Lives Matter movement, a

Today's guest is psychologist and behavioral scientist, Wendy Wood. She is currently a professor of psychology and business at the University of Southern California, and a visiting professor at the INSEAD Business School in Paris. Wendy has spent much of her career studying what she considers the very building blocks of behavioral change, something we all know as habits. Angela Duckworth describes her as “the world's foremost expert in the field.” And according to Adam Grant, she is “widely recognized as the authority on the science of habits,” We'll explore her research and recent book, Good Habits, Bad Habits: The Science of Making Positive Changes That Stick (Farrar, Straus and Giroux) Colin Miller and Dr. Keith Mankin host the popular medical podcast, PeerSpectrum. Colin works in the medical device space and Keith is a retired pediatric orthopedic surgeon. Learn more about your ad choices. Visit megaphone.fm/adchoices

After his father died, James L. Nolan, Jr., took possession of a box of private family materials. To his surprise, the small secret archive contained a treasure trove of information about his grandfather’s role as a doctor in the Manhattan Project. Dr. Nolan, it turned out, had been a significant figure. A talented ob-gyn radiologist, he cared for the scientists on the project, organized safety and evacuation plans for the Trinity test at Alamogordo, escorted the “Little Boy” bomb from Los Alamos to the Pacific Islands, and was one of the first Americans to enter the irradiated ruins of Hiroshima and Nagasaki. Participation on the project challenged Dr. Nolan’s instincts as a healer. He and his medical colleagues were often conflicted, torn between their duty and desire to win the war and their oaths to protect life. Atomic Doctors: Conscience and Complicity at the Dawn of the Nuclear Age (Harvard UP, 2020) follows these physicians as they sought to maximize the health and safety of those exposed to nuclear r

Addiction occurs among physicians at the same rate as in the general population, about 10%. Unlike the general population, however, an intensive rehabilitation program, geared specifically for their profession, vastly improves their chances of finding long-term sobriety. Over 70% of these physicians will be clean and sober-and practicing medicine-five years later. How is this achieved, and can these principles be applied to anyone? A Spiritual Pathway to Recovery from Addiction: A Physician’s Journey of Discovery (The Meadows Farm, Inc.) is the memoir of a group of physicians going through an intensive rehab program for addiction to drugs and alcohol. It is presented as a collection of their stories and the lessons they encountered during their time together. As they proceed on a course of personal self-discovery, they share their past experiences, fears, and hopes. As the lessons of recovery begin to sink in, their thinking and behavior change from that of a self-absorbed ego-driven wreck to someone capable

Today's guest is Christopher Robertson, Associate Dean for Research and Innovation and Professor of Law at the University of Arizona. His background and research interests overlap several academic disciplines, including bioethics, health law, incentives, behavioral economics and more. His CV includes a PhD in philosophy and a law degree from Harvard. His newest book is Exposed: Why Our Health Insurance is Incomplete and What can be Done About (Harvard University Press, 2019). Colin Miller and Dr. Keith Mankin host the popular medical podcast, PeerSpectrum. Colin works in the medical device space and Keith is a retired pediatric orthopedic surgeon. Learn more about your ad choices. Visit megaphone.fm/adchoices

Hidden Valley Road: Inside The Mind of An American Family (Doubleday, 2020) is the story of a midcentury American family with twelve children, six of them diagnosed with schizophrenia, that became science's great hope in the quest to understand the disease. Don and Mimi Galvin seemed to be living the American dream. After World War II, Don's work with the Air Force brought them to Colorado, where their twelve children perfectly spanned the baby boom: the oldest born in 1945, the youngest in 1965. In those years, there was an established script for a family like the Galvins--aspiration, hard work, upward mobility, domestic harmony--and they worked hard to play their parts. But behind the scenes was a different story: psychological breakdown, sudden shocking violence, hidden abuse. By the mid-1970s, six of the ten Galvin boys, one after another, were diagnosed as schizophrenic. How could all this happen to one family? What took place inside the house on Hidden Valley Road was so extraordinary that the Galvins b

Everyday suffering—those conditions or feelings brought on by trying circumstances that arise in everyone’s lives—is something that humans have grappled with for millennia. But the last decades have seen a drastic change in the way we approach it. In the past, a person going through a time of difficulty might keep a journal or see a therapist, but now the psychological has been replaced by the biological: instead of treating the heart, soul, and mind, we take a pill to treat the brain. Chemically Imbalanced: Everyday Suffering, Medication, and Our Troubled Quest for Self-Mastery (University of Chicago Press) is a field report on how ordinary people dealing with common problems explain their suffering, how they’re increasingly turning to the thin and mechanistic language of the “body/brain,” and what these encounters might tell us. Drawing on interviews with people dealing with struggles such as underperformance in school or work, grief after the end of a relationship, or disappointment with how their life is

In Merchants of Medicine: The Commerce and Coercion of Health in Britain’s Long Eighteenth Century (The University of Chicago Press), medicines embody the hopes of those who prepared, sold, and ingested them. By investigating the different contexts and practices associated with the British long-distance trade in patent medicines, Zachary Dorner unravels the intertwined history of financial markets, health concerns, and colonial warfare. He argues that from the late seventeenth-century, medicines were produced, distributed, and consumed in new ways, providing solutions to the problems of labor shortages in the armed forces, trading companies and plantations, while also informing the categories of difference that organized such institutions. Zachary Dorner is the Patrick Henry Postdoctoral Fellow in history at Johns Hopkins University. Learn more about your ad choices. Visit megaphone.fm/adchoices

Today’s guest is investigative journalist and author, Gerald Posner. His new book, Pharma: Greed, Lies, and the Poisoning of America (Simon and Schuster), explores the fascinating and complex history of pharmaceutical and bio-tech industries. It is an industry like no other and a story like no other. Gerald Posner is an award-winning journalist who has written twelve books, including the Pulitzer Prize finalist Case Closed and multiple national bestsellers. Colin Miller and Dr. Keith Mankin host the popular medical podcast, PeerSpectrum. Colin works in the medical device space and Keith is a retired pediatric orthopedic surgeon. Learn more about your ad choices. Visit megaphone.fm/adchoices

Today’s guest is journalist and author, Wendy Moore. Her new book, No Man’s Land: The Trailblazing Women Who Ran Britain's Most Extraordinary Military Hospital During World War I (Basic Books) explores the WWI British military hospital known as Endell Street. A hospital run by two suffragette doctors, Louisa Garrett Anderson and Flora Murray. A hospital staffed almost completely by women who treated over 26,000 wounded soldiers. It’s an incredible book published by Atlantic Books in the UK and Basic Books in the US, in April 2020. Wendy Moore is a journalist and author of several previous books, including How to Create the Perfect Wife and Wedlock, a Sunday Times bestseller. Colin Miller and Dr. Keith Mankin host the popular medical podcast, PeerSpectrum. Colin works in the medical device space and Keith is a retired pediatric orthopedic surgeon. Learn more about your ad choices. Visit megaphone.fm/adchoices

Outbreaks of Ebola, SARS, MERS, and pandemic influenza are brutal reminders of the dangers of infectious disease. Comparing the development of disease control in Britain and the United States, from the 1793 yellow fever outbreak in Philadelphia to the H1N1 panics of more recent times, Diseased States: Epidemic Control in Britain and the United States (University of Massachusetts Press) provides a blueprint for managing pandemics in the twenty-first century. To understand why these two nations have handled contemporary disease threats in such different ways, Charles Allan McCoy examines when and how disease control measures were adopted in each country from the nineteenth century onward, which medical theory of disease was dominant at the time, and where disease control was located within the state apparatus. Particular starting conditions put Britain and the United States on distinct trajectories of institutionalization that led to their respective systems of disease control. As McCoy shows, even the seemingl

Why Do Unnecessary and Often Counter-Productive Medical Interventions Happen So Often? Today I talked to Paul Offit about his book Overkill: When Modern Medicine Goes Too Far (HarperCollins, 2020) Offit is a professor of pediatrics at the University of Pennsylvania and the director of the Vaccine Education Center at the Children’s Hospital of Philadelphia. A prolific author, he’s also well known for being the public face of the scientific consensus that vaccines have no association with autism. Topics covered in this episode include: The degree to which opportunities to make money and avoid law suits drives the behavior of doctors, though inertia and unwillingness to accept advances in knowledge are also common explanations for being at times too active in treating patients. How the marketing campaigns of pharmaceutical companies can warp treatment plans. The conclusions from countless studies that in at least the 15 common medical interventions covered in this book, many patients are better off with more

While the eradication of smallpox has long been documented, not many know the Chinese roots of this historic achievement. In this revelatory study, Mass Vaccination. Citizens' Bodies and State Power in Modern China (Cornell University Press), Mary Augusta Brazelton examines the PRC's public health campaigns of the 1950s to explain just how China managed to inoculate almost six hundred million people against this and other deadly diseases. Mass Vaccination tells the story of the people, materials, and systems that built these campaigns, exposing how, by improving the nation's health, the Chinese Communist Party quickly asserted itself in the daily lives of all citizens. This crusade had deep roots in the Republic of China during the Second Sino-Japanese War, when researchers in China's southwest struggled to immunize as many people as possible, both in urban and rural areas. But its legacy was profound, providing a means for the state to develop new forms of control and of engagement. Brazelton considers the i

Every year nine million people are diagnosed with tuberculosis, every day over 13,400 people are infected with AIDs, and every thirty seconds malaria kills a child. For most of the world, critical medications that treat these deadly diseases are scarce, costly, and growing obsolete, as access to first-line drugs remains out of reach and resistance rates rise. Rather than focusing research and development on creating affordable medicines for these deadly global diseases, pharmaceutical companies instead invest in commercially lucrative products for more affluent customers. Nicole Hassoun argues that everyone has a human right to health and to access to essential medicines, and she proposes the Global Health Impact (global-health-impact.org/new) system as a means to guarantee those rights. Her proposal directly addresses the pharmaceutical industry's role: it rates pharmaceutical companies based on their medicines' impact on improving global health, rewarding highly-rated medicines with a Global Health Impact l