New Books In Medicine

Today's guest is David Sinclair, professor of genetics at Harvard Medical School and co-director of the Paul Glenn Center Biological Mechanisms of Aging. He is widely considered on the world's foremost experts on longevity research. A co-founder of the journal Aging and several biotech companies, he also hold 35 patents. Dr. Sinclair is a recipient of more than 25 awards and honors, including being knighted in the Order of Australia. His work is featured in five books, two documentary movies, “60 Minutes,” Morgan Freeman’s “Through the Wormhole,” and other media. His newest book, LifeSpan. Why We Age and Why We Don't Have To, was released in September 2019 by Simon and Schuster.Colin Miller and Dr. Keith Mankin host the popular medical podcast, PeerSpectrum. Colin works in the medical device space and Keith is a retired pediatric orthopedic surgeon.Learn more about your ad choices. Visit megaphone.fm/adchoices

Nora Jaffary’s Reproduction and its Discontents in Mexico: Childbirth and Contraception from 1750 to 1905 (University of North Carolina Press. 2016), tracks how medical ideas, practices, and policies surrounding reproduction changed between the late eighteenth and early twentieth centuries in Mexico. Perhaps the most important change analyzed in the book, and discussed extensively in the interview, is the increased interest of the state in controlling childbirth and contraception. Whereas the colonial state was mostly interested in controlling reproduction primarily of Spanish women of the elite, in the republican era—specially in the late nineteenth century—the state expanded its scope in order to reach broader and more popular sectors of women. Abortion and infanticide, treated jointly in the book for people did not draw a distinction between them, came under the purview of communities and the state. We learn that family members, lovers and neighbors started denouncing women more frequently, and that crimin

Not a lot of authors go from spending their early twenties homeless and addicted to cocaine to becoming one of the world’s leading researchers on the neuroscience of addiction. But Dr. Judith Grisel, in her new book Never Enough: The Neuroscience and Experience of Addiction (Doubleday, 2019), uses her personal story to illuminate the ways in which the brain, in collusion with social and biological factors, makes addiction possible. In our discussion, Grisel outlines the effects of different drugs, explains the “three laws of psychopharmacology,” and wonders if we’ll ever find medicine’s “holy grail” – a cure for addiction. Emily Dufton is the author of Grass Roots: The Rise and Fall and Rise of Marijuana in America (Basic Books, 2017). A drug historian and writer, she edits Points, the blog of the Alcohol and Drugs History Society. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

On a spring day in 2015, Dr. Travis Rieder’s life changed. A motorcycle accident, a shattered foot, and a long series of surgeries later, the John Hopkins University bioethicist had a far deeper understanding of opioid use in America than he ever planned. In his new book In Pain: A Bioethicist’s Personal Struggle with Opioids(Harper Collins, 2019), Rieder shares the story of his accident and treatment, while also exploring the complicated history of opioid use in the United States, the challenge of treating something as subjective as pain, and alternatives to our reliance on these drugs. His recommendations—for medical practitioners and for individual patients—are insightful and necessary as America continues to grapple with the unanticipated effects of widespread opioid use.Emily Dufton is a drug historian and the author of Grass Roots: The Rise and Fall and Rise of Marijuana in America (Basic Books, 2017).  Learn more about your ad choices. Visit megaphone.fm/adchoices

Environmental racism is visible not only as cancer clusters or the location of grocery stores. It is responsible for the reported gap in IQ scores between white Americans and Black, Latinx, and Native Americans. So argues science writer Harriet Washington in A Terrible to Waste: Environmental Racism and Its Assault on the American Mind (Little, Brown Spark 2019). While acknowledging IQ is a biased and flawed metric, she contends it is useful for tracking cognitive damage. Using copious data and synthesizing a generation of studies, Washington calculates the staggering, population-scale neurological effects of marginalized communities having been forced to live and work in landscapes of waste, pollution, and insufficient sanitation services. She investigates heavy metals, neurotoxins, asthma, deficient prenatal care, bad nutrition, and even pathogens as drags on cognitive development to explain why communities of color are disproportionately affected—and what can be done to remedy this devastating problem. Har

Once upon a time, or so we’ve been told, medical ethics were confined to the patient-doctor relationship. As long as doctors were true to their Hippocratic oaths, as long as they acted with compassion and wisdom, then all expectations were met.Life is more complicated today, and so is healthcare: an undertaking, like all others, that is influenced by social, political, legal and cultural factors.Nothing is value-free.In Bioethics and Biopolitics in Israel: Socio-legal, Political and Empirical Analysis (Cambridge University Press, 2019), Professor Shai Lavi and his colleagues have produced a groundbreaking work that offers a novel understanding of Israeli bioethics. It is a milestone in the comparative literature of bioethics.Bringing together a range of experts, the book's interdisciplinary structure employs a contemporary, sociopolitical-oriented approach to bioethics issues, with an emphasis on empirical analysis, that will appeal not only to scholars of bioethics, but also to students of law, medicine, hum

Are we in the midst of a psychedelic renaissance? If so, what can we learn about the present moment through the history of psychedelic experiments in the past? Matt Oram discusses contemporary debates about LSD and MDMA and brings much-needed context with his new book, The Trials of Psychedelic Therapy: LSD Psychotherapy in America (Johns Hopkins University Press, 2018), Oram talks about the role of psychiatry and the pharmaceutical industry as well the field of drug regulation. He underlines, too, that the history of psychedelics is a lot more complicated than researchers have previously suggested. Lucas Richert is an associate professor in the School of Pharmacy at the University of Wisconsin, Madison. He studies intoxicating substances and the pharmaceutical industry. He also examines the history of mental health. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine

In 1978, doctors in Denver, Colorado observed several healthy children who suddenly and mysteriously developed a serious, life-threatening illness with no visible source. Their condition, which doctors dubbed ‘toxic shock syndrome’ (TSS) was rare, but observed with increasing frequency over the next few years in young women, and was soon learned to be associated with a bacterium and the use of high-absorbency tampons that had only recently gone on the market. In 1980, the Centers for Disease Control identified Rely tampons, produced by Procter & Gamble, as having the greatest association with TSS over every other tampon, and the company withdrew them from the market. To this day, however, women are frequently warned about contracting TSS through tampon use, even though very few cases are diagnosed each year.Historian Sharra Vostral’s Toxic Shock: A Social History (NYU Press, 2018) is the first and definitive history of TSS. Vostral shows how commercial interests negatively affected women’s health outcomes

Okezi Otovo’s Progressive Mothers, Better Babies: Race, Public Health, and the State in Brazil, 1850-1945 (U Texas Press, 2016) explores the intersecting histories of race, gender, and class in modern Brazil. Between 1850 and 1945, the period covered in the book, Brazil experienced a range of profound socio-political transformations: from the end of the transatlantic slave trade (1850), to the wholesale abolition of slavery (1988), the demise of the monarchy followed by the rise of a republican system of government, and the ultimate inauguration of the Vargas dictatorship. Set in Bahia, the book considers the impact of these changes in the lives of black mothers and their children by following the rise of the maternalist movement in Brazil and its relationship to international discourses on race, public health reform, and national modernity. In addition to tracking changes to medical ideas about motherhood and children, Okezi Otovo gives agency to these black and brown mothers and considers both how they acte

How do women -- especially poor and low-income women with histories of childhood sexual trauma and drug addiction -- respond to and deal with an HIV/AIDS diagnosis? How do some manage to not merely rebuild their lives, but remake them entirely? Why do others fail? Join us to talk to Celeste Watkins-Hayes about her book Remaking a Life: How Women Living with HIV/AIDS Confront Inequality(University of California Press, 2019). You'll hear what she learned from a decade’s long immersion in the lives of these remarkable women, and what lessons that has to offer to politicians, policymakers, and service-providers.Stephen Pimpare is Senior Lecturer in the Politics & Society Program and Faculty Fellow at the Carsey School of Public Policy at the University of New Hampshire. He is the author of The New Victorians (New Press, 2004), A People’s History of Poverty in America (New Press, 2008), winner of the Michael Harrington Award, and Ghettos, Tramps and Welfare Queens: Down and Out on the Silver Screen (Oxford, 20

Vanessa Heggie talks about the history of biomedical research in extreme environments. Heggie is a Fellow of the Institute for Global Innovation at the University of Birmingham. She is the author of Higher and Colder: A History of Extreme Physiology and Exploration(University of Chicago Press, 2019).During the long twentieth century, explorers went in unprecedented numbers to the hottest, coldest, and highest points on the globe. Taking us from the Himalaya to Antarctica and beyond, Higher and Colder presents the first history of extreme physiology, the study of the human body at its physical limits. Each chapter explores a seminal question in the history of science, while also showing how the apparently exotic locations and experiments contributed to broader political and social shifts in twentieth-century scientific thinking.Unlike most books on modern biomedicine, Higher and Colder focuses on fieldwork, expeditions, and exploration, and in doing so provides a welcome alternative to laboratory-dominated acc

Personalized healthcare―or what the award-winning author Donna Dickenson calls "Me Medicine"―is radically transforming our longstanding "one-size-fits-all" model. Technologies such as direct-to-consumer genetic testing, pharmacogenetically developed therapies in cancer care, private umbilical cord blood banking, and neurocognitive enhancement claim to cater to an individual's specific biological character, and, in some cases, these technologies have shown powerful potential. Yet in others they have produced negligible or even negative results. Whatever is behind the rise of Me Medicine, it isn't just science. So why is Me Medicine rapidly edging out We Medicine, and how has our commitment to our collective health suffered as a result?In her cogent, provocative book Me Medicine vs. We Medicine: Reclaiming Biotechnology for the Common Good(Columbia University Press, 2016), Dickenson examines the economic and political factors fueling the Me Medicine phenomenon and explores how, over time, this paradigm shift in

Alex Broadbent's Philosophy of Medicine (Oxford University Press, 2019)  asks two central questions about medicine: what is it, and what should we think of it? Philosophy of medicine itself has evolved in response to developments in the philosophy of science, especially with regard to epistemology, positioning it to make contributions that are medically useful. This book locates these developments within a larger framework, suggesting that much philosophical thinking about medicine contributes to answering one or both of these two guiding questions.Taking stock of philosophy of medicine's present place in the landscape and its potential to illuminate a wide range of areas, from public health to policy, Alex Broadbent introduces various key topics in the philosophy of medicine. The first part of the book argues for a novel view of the nature of medicine, arguing that medicine should be understood as an inquiry into the nature and causes of health and disease. Medicine excels at achieving understanding, bu

The AIDS crisis of the 1980s looms large in recent histories of sexuality, medicine, and politics, and justly so—an unknown virus without a cure ravages an already persecuted minority, medical professionals are unprepared and sometimes unwilling to care for the sick, and a national health bureaucracy is slow to invest resources in finding a cure. Yet this widely accepted narrative, while accurate, creates the impression that the gay community lacked any capacity to address AIDS. In fact, as Katie Batza demonstrates in this path-breaking book, there was already a well-developed network of gay-health clinics in American cities when the epidemic struck, and these clinics served as the first responders to the disease. Before AIDS: Gay Health Politics in the 1970s (University of Pennsylvania Press, 2018) explores this heretofore unrecognized story, chronicling the development of a national gay health network by highlighting the origins of longstanding gay health institutions in Boston, Chicago, and Los Angeles, pl

Could cancer be a contagious disease? Although this possibility might seem surprising to many of us, it has a long history. In fact, efforts to develop a cancer vaccine drew more money than the Human Genome Project. In his first book, MIT historian of science Robin Wolfe Scheffler takes readers through the twists and turns of the American effort to identify human cancer viruses— a search which made fundamental contributions to molecular biology. In this podcast, we discuss how this was an effort which raises fundamental questions regarding how we think about disease in the laboratory and the legislature.Dr. Robin Scheffler’s book is called A Contagious Cause: The American Hunt for Cancer Viruses and the Rise of Molecular Medicine(University of Chicago Press, 2019).Dr. Dorian Deshauer is a psychiatrist, historian, and assistant professor at the University of Toronto. He is associate editor for the Canadian Medical Association Journal, Canada’s leading peer-reviewed general medical journal and is one of the hos

Paul Ramírez’s first book explores how laypeople impacted the new medical techniques and technologies implemented by the imperial state in the final decades of Spanish rule in colonial Mexico.  More than a scholarly intervention, Ramírez seeks to answer a very pragmatic and timely question: how and why do successful public health measures succeed?  Through his surprising, nuanced, and complicated answer, Ramírez broadens our understanding of who counts as a vital actor in public health programs.  Whereas historians have long thought of enlightened reform in the terms of absolutist monarchical power, Enlightened Immunity: Mexico’s Experiments with Disease Prevention in the Age of Reason (Stanford University Press, 2018)cracks the nut to find within a effervescent world of competitive and cooperative medical cultures. Through careful analyses of the Royal Vaccination Campaign of the early 19th century as well as prior public methods of responding to epidemic disease, Ramírez demonstrates a consis

Too often keeping patients alive gets in the way of helping them as they approach death. Dr. Pauline Chen shares her experiences as a medical student and transplant surgeon and how they’ve shaped the way she practices medicine.Chen is the author of Final Exam: A Surgeon’s Reflections on Mortality (Vintage, 2008) and the New York Times column “Doctor and Patient.” Her essays have appeared in The Washington Post, The New York Times Magazine, and The New York Times Book Review. Her work has been nominated for a National Magazine Award.Michael F. Robinson is professor of history at Hillyer College, University of Hartford. He's the author of The Coldest Crucible: Arctic Exploration and American Culture (University of Chicago Press, 2006) and The Lost White Tribe: Scientists, Explorers, and the Theory that Changed a Continent (Oxford University Press, 2016). He's also the host of the podcast Time to Eat the Dogs, a weekly podcast about science, history, and exploration. Learn more about your ad choices. Visit

Nara Milanich’s Paternity: The Elusive Quest for the Father (Harvard University Press, 2019) explains how fatherhood, long believed to be impossible to know with certainty, became a biological “fact” that could be ascertained with scientific testing. Though the advent of DNA testing might seem to make paternity less elusive, Milanich’s book invites readers to think about paternity not as a biological fact but as a socially-constructed role that has evolved over time. Historically, given assumed paternal uncertainty, fathers were defined in terms of their behavior (acting like a father) or their relationship to a child’s mother (being married to a woman made a man the father of her offspring). In the twentieth century, paternity testing developed as a way to scientifically determine male progenitors, although these new methods never replaced older ways of reckoning paternity. Milanich describes blood tests and other early techniques proffered by doctors and scrutinized by courts as a way to know the “true” fat

Why did Ebola, a virus so deadly that it killed or immobilized its victims within days, have time to become a full-blown epidemic? That’s what happened in 2013 in when the virus, already well-known to virologists and epidemiologists, broke out in West Africa, infecting twenty-eight thousand people and killing eleven thousand.Stephan Bullard, associate professor of biology at the University of Hartford, discusses the 2013 outbreak which is the subject of his new book, A Day to Day Chronicle of the 2013-16 Ebola Outbreak, now out with Springer Press (2018).Michael F. Robinson is professor of history at Hillyer College, University of Hartford. He's the author of The Coldest Crucible: Arctic Exploration and American Culture (University of Chicago Press, 2006) and The Lost White Tribe: Scientists, Explorers, and the Theory that Changed a Continent (Oxford University Press, 2016). He's also the host of the podcast Time to Eat the Dogs, a weekly podcast about science, history, and exploration.Learn more about your a

Today I talked with historian Erika Dyck about Aldous Huxley, Humphry Osmond and their correspondence over a ten year period. Psychedelic Prophets: The Letters of Aldous Huxley and Humphry Osmond (McGill-Queen's University Press, 2018) is a collection of letters which were carefully curated by Erika and Cynthia Carson Bisbee, Paul Bisbee, and Patrick Farrell. During our discussion, Erika recounts the special relationship between two intellectual juggernauts, Huxley and Osmond, and their discussions about drugs, addiction, and death and dying. This important set of letters raises fascinating questions about medicines, the "psychedelic renaissance," the nature of the mind, and perceptions of reality. Dyck is the author of Psychedelic Psychiatry: LSD From Clinic to Campus (Johns Hopkins UP, 2010) as well as Culture's Catalyst: Historical Encounters with Peyote and the Native American Church in Canada (Manitoba, 2017). Lucas Richert is an associate professor in the School of Pharmacy at the University of Wisconsi