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With human papillomavirus vaccine in short supply around, moving from a three- or two-dose regimen to one dose would immediately double or treble supplies, cut costs, and simplify logistics. A careful study in Cancer by this week’s guest, Ana Rodriguez, and her colleagues adds to the evidence that single-dosing is possible and protective against pre-cancerous cervical lesions. Cancer article Cancer editorial  An earlier (2015) podcast on the question of the number of vaccine doses needed to confer protection Running time: 16 minutes The post Podcast 253: Is a single-dose HPV vaccination effective? first appeared on Clinical Conversations.