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A JAMA paper suggests that in all but the most severe exacerbations of COPD, it’s best to start off with low-dose oral corticosteroids rather than the higher-dose intravenous treatment that, contrary to guideline recommendations, almost everyone now gets. Our conversation this week is with the study’s first author, Dr. Peter Lindenauer. Visit the Journal Watch website at http://jwatch.org for a comprehensive look at new medical research, with comments from our experts. Interview-related links: COPD guidelines from the Global Initiative for Chronic Obstructive Lung Disease JAMA article abstract News-related links: Increased cancer risk with ARBs Diabetes, its treatments, and cancer risks FDA announces review of olmesartan FDA’s MedWatch reporting site The post Podcast 92: Corticosteroids in COPD exacerbations — high-dose intravenous or low-dose oral? first appeared on Clinical Conversations.