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Patients with hypertension at risk for cardiovascular events have done better with an ACE inhibitor-calcium channel blocker combination than with the ACE inhibitor plus hydrochlorothiazide. The ACCOMPLISH investigators have now reported on their analysis of progression-of-nephropathy outcomes in their trial. We interview the first author of the analysis, Dr. George Bakris of the University of Chicago’s Pritzker School of Medicine. Interview-related links: NHLBI guidelines on managing hypertension Physician’s First Watch coverage of ACCOMPLISH analysis News-related links: FDA warning on long-acting beta agonists Pipe- and cigar-smoking and COPD risk Metformin’s sometimes-offputting aroma Health statistics on the U.S. The post Podcast 75: Which regimen for hypertension? first appeared on Clinical Conversations.