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We talk with Drs. Michael Mauer, Ronald Klein, and Bernard Zinman about their paper in the July 2 New England Journal of Medicine reporting on the RASS study (Renin-Angiotensin System Study). They found that blockade of the renin-angiotensin system was not effective in the primary prevention of diabetic nephropathy in Type 1 diabetes. This week’s news links: Darvon, Darvocet to Get Stronger Warnings on Fatal Overdose Risk Famotidine Associated with Fewer GI Complications from Low-Dose Aspirin Dronedarone Approved for Maintenance Therapy in Atrial Fibrillation and Atrial Flutter The week’s interview links: Renal and Retinal Effects of Enalapril and Losartan in Type 1 Diabetes The post Podcast 49: Three RASS Study researchers discuss their findings on the lack of benefit of renin-angiotensin blockade in the primary prevention of diabetic nephropathy in Type 1 diabetes. first appeared on Clinical Conversations.