Niners Nation: For San Francisco 49ers Fans

49ers in Five: Isaac Guerendo WILL play tonight vs. the Rams San Francisco 49ers RB Isaac Guerendo will try and play on a foot sprain against the Los Angeles Rams, according to Adam Schefter. Plus, George Kittle predicts a breakout game for Deebo Samuel, and Brock Purdy scouts the Rams defense. One Thing to Read: https://www.espn.com/nfl/insider/story/_/id/42910575/2025-offseason-moves-fix-49ers-bengals-cowboys-jets-trades-cuts-firings-signings CHECK OUT AURA FRAMES! Save on the perfect gift by visiting AuraFrames.com to get $35-off Aura’s best-selling Carver Mat frames by using promo code [GOLD] at checkout. That’s A-U-R-A Frames.com promo code [GOLD]. This deal is exclusive to listeners, so get yours now in time for the holidays! Terms and conditions apply. CHECK OUT UNDERDOG FANTASY: Sign up and deposit for Underdog HERE with promo code GOLDSTANDARD to get up to $1,000 in bonus cash and a free pick: underdogfantasy.com or download the app. Must be 18+ (19+ AL, Nebraska; 19+ in CO for some games, 21+MA