Middle Tech

Lepidext is a Lexington-based biotech company developing a natural, non-chemical solution to control one of agriculture’s most damaging pests - the corn earworm. Founded by Dr. Bruce Webb, a University of Kentucky professor emeritus and virus researcher, Lepidext uses a modified virus to sterilize pest populations without harming the environment.The technology originated from research into a major equine reproductive crisis in Kentucky and evolved into a scalable product with the potential to replace traditional pesticides in the field. With a regulatory decision pending from the EPA, Lepidext is preparing for commercial rollout with a focus on farmer partnerships and sustainable impact.In this episode, Bruce and research scientist Dr. Mary Wallace share the journey from university research to ag-tech startup, the science behind their approach, and what’s next for Lepidext as they bring biological pest control to market.Expect to learn how a virus discovered in nature became the foundation for a new kind of p

This episode marks Part 1 of a special mini-series - produced by Middle Tech in collaboration with the GAME Change coalition. Over the course of three episodes, we’ll explore how Kentucky and Tennessee are working to become a national hub for circular economy innovation and sustainable manufacturing. This initiative is part of a regional effort to secure a $160 million grant from the National Science Foundation’s Engines Program.Two years ago, a small group of visionaries began mapping out a bold idea: to build the U.S. innovation hub for circular economy technologies right here in the Southeast Commerce Corridor. That idea has grown into GAME Change - a 400+ member coalition of universities, national labs, policy leaders, and private industry partners reshaping the future of manufacturing in Kentucky and Tennessee.Middle Tech has been closely embedded in this journey from the start, documenting key moments, stakeholder voices, and the growing momentum behind a new vision for regional economic developmentGAME

Silas Deane is a founder, serial entrepreneur, and University of Kentucky graduate who bootstrapped his company, VendEngine, from a back-of-the-napkin idea to an $84 million exit. VendEngine serves correctional facilities, providing a solution that transforms how families support incarcerated loved ones. With no outside funding, Silas grew the company steadily over 12 years, leading to an $84 million acquisition by Tyler Technologies. His accomplishments recently earned him a place in UK's Gatton College of Business and Economics Hall of Fame, a recognition of his successes since his time at UK.In this episode, Silas shares how he navigated the Dot-Com boom and bust, the challenges of bootstrapping a tech company, and the strategies he used to scale VendEngine in a complex industry. Expect to learn how Silas approached building technology solutions for underserved markets, why he never raised capital for the business, and what advice he has for entrepreneurs looking to grow without outside capital.Middle Tech

Nick Touran is a nuclear engineer, educator, and advocate who spent nearly 16 years designing advanced reactors at TerraPower and building one of the most trusted resources in nuclear education, WhatIsNuclear.com. Now, he’s on a mission to help America rethink its relationship with nuclear energy - and its future.What would it take for nuclear to fuel America's next era of innovation? Why did we fall behind - and can we catch up before it's too late?Expect to learn why Nick believes a nuclear renaissance is critical for the U.S., how China’s aggressive investment in nuclear is reshaping global energy leadership, the biggest myths still holding nuclear back, the reality behind nuclear waste and radiation fears, and why advanced reactor designs could change everything.Middle Tech is proudly supported by:KY Innovation → kyinnovation.com

In this episode, we’re joined by Courtland Leer, co-founder of Plastic Labs, to explore how AI can be made more personal, contextual, and aligned to individual users. Courtland walks us through his team’s mission to “decentralize alignment” and build agents that don’t just process inputs - they understand who you are.We dive into:- The philosophy and tech behind Honcho, a natural language memory layer for AI apps.- Why post-training alignment is more scalable and flexible than pre-training.- How synthetic identity lets agents model users more accurately.- The link between education and AI—and how Courtland’s background as a teacher shapes his thinking.- A wild story about meme coins, agent grants, and AI agents with crypto wallets.This one goes deep on AI, identity, education, and the frontier of decentralized tech. If you’re building in the AI space or thinking about the future of human-agent collaboration, don’t miss it.

Brad Luttrell is a founder and storyteller who recently made the difficult decision to shut down his company, GoWild. Now, he’s building again—with more focus and experience behind his new company, Prologue.What actually happens when a startup fails? How do founders know when it’s time to pull the plug—and what comes next?Expect to learn how Brad came to the decision to shut down GoWild, what it felt like to have not one, but two 8-figure acquisition offers fall through, the lessons he’s carrying into Prologue, how he approached fundraising differently the second time around, and why starting again doesn’t mean starting from scratch.

Valvoline is known for its long history in automotive lubricants, but today, the company is pushing into a new frontier: data centers. As the demand for artificial intelligence grows and more data centers come online, the energy-intensive chips that power AI models are facing an overheating crisis. Enter Valvoline.In this episode, we sit down with Dr. George Zhang, VP of Research and Development, and Michael Morrison, Director of New Ventures at Valvoline, to explore how the company is leveraging its expertise in heat transfer to cool next-generation data centers.Our conversation covers the science behind liquid cooling and why AI chips are overheating, how Valvoline is adapting its lubricant technology for data center cooling, and the role of Kentucky in Valvoline’s innovation efforts.

Logan and Evan sit down with Kentucky Governor Andy Beshear to discuss Kentucky’s economic development successes, private sector investment, and the role of innovation in shaping Kentucky's future.Under Governor Beshear’s administration, Kentucky has seen over $35 billion in private sector investment - more than any governor in Kentucky history - including major projects in battery manufacturing, infrastructure, and technology. Our conversation explores:- What’s driving business investment in Kentucky- The economic impact of projects like the BlueOval SK Battery Park and AESC Gigafactory- How the state is supporting innovation, startups, and workforce developmentWe’re excited to spotlight the impact of innovation on Kentucky’s economic future!Help Eastern Kentucky Flood Victims: Donate to Kentucky’s Storm Relief Fund Support New Frontier's Kentucky Strong Campaign (100% of proceeds support relief efforts)Additional Flood Resources

Middle Tech is back for Season 8! In this episode, Logan and Evan dive into major personal and business updates, including Logan’s decision to go full-time with Middle Tech & DevelopLex and Evan’s launch of Valent, his startup leveraging AI to accelerate RFP responses.They discuss the vision for 2025, upcoming high-production episodes, and the expansion of Middle Tech’s role in Kentucky’s innovation ecosystem. The conversation covers:✅ Why Logan left Fooji to go all-in on Middle Tech✅ Evan’s journey from Simba to launching Valent with over $1M raised✅ The evolution of DevelopLex & how it fits into Kentucky’s economic future✅ The rise of AI meetups & workshops—why they’re critical for Kentucky✅ What’s changing in our content strategy and events for 2025We’re making big moves this year, and we want you to be part of it!

On today's episode, we welcome back Colby Hall, the executive director of SOAR. SOAR was recently awarded $40 million through a grant from the U.S. Economic Development Administration, focused on revamping EKY's economic identity. We dive into the challenges of employment gaps in Eastern Kentucky, the importance of remote work, and how the geography of the region has impacted it's economic development. Colby emphasizes the need for a new economic identity, the role of entrepreneurship, and the success of the SOAR Summit in fostering innovation in the Appalachian region. Looking ahead, he shares his vision for the future and the importance of individual support in driving community change. To learn more about SOAR and the grant they were awarded, you can check out this press release: https://soar-ky.org/soar-eda-recompete/ Be the first to see new episodes, along with a summary, key takeaways, and upcoming events, by subscribing to Middle Tech's Spotlight Series Newsletter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://middletech.

In this episode, Logan Jones and Evan Knowles sit down with Monica Bilak, Executive Director of Sprocket Innovation, to discuss the growing startup ecosystem in Western Kentucky. Monica shares her diverse career journey, from managing microgrants in East Africa to leading community revitalization projects and now spearheading Sprocket Innovation in Paducah, Kentucky.The conversation highlights the unique challenges and opportunities of fostering innovation in a smaller regional ecosystem and how Sprocket supports entrepreneurs with programs like the West Kentucky Innovation Challenge and Next 50k. Monica emphasizes the importance of leveraging local resources, building strong networks, and collaborative efforts among Kentucky’s innovation hubs.The episode also delves into the future of entrepreneurship in Western Kentucky, focusing on the potential growth sectors and the role of regional storytelling and networking. Be the first to see new episodes, along with a summary, key takeaways, and upcoming events, b

In this episode, we explore the entrepreneurial journey of Destin George Bell, the founder behind the Card.io app, a gamified fitness platform that combines elements of Capture the Flag with fitness tracking. From his roots in Louisville to establishing his startup in Austin, Destin shares the challenges and triumphs of launching a business during the pandemic and his experience pitching on Shark Tank. We dive into how Destin started down the path of entrepreneurship while at UK, the role that self-taught hustle and community support played along the way, and what he hopes to accomplish with Card.io in the near future. Be the first to see new episodes, along with a summary, key takeaways, and upcoming events, by subscribing to Middle Tech's Spotlight Series Newsletter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://middletech.beehiiv.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Get in touch in the comments below, or reach out to us on social media: Twitter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.twitter.com/middletechpod⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.in

In this episode recorded live at the 2024 SOAR Summit, we talk with Cindy Sparks from Complete3D and Dr. Elijah Jensen from Black Box Energy Systems - two former winners of the Appalachia startup pitch competition. We discuss how Black Box Energy Systems is innovating in the energy sector with lightweight, efficient power solutions, and how Complete3D is making 3D printing accessible through maintenance and education. Learn about the challenges they faced, the entrepreneurial spirit that drives them, and the unique opportunities Kentucky offers for startups. Be the first to see new episodes, along with a summary, key takeaways, and upcoming events, by subscribing to Middle Tech's Spotlight Series Newsletter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://middletech.beehiiv.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Get in touch in the comments below, or reach out to us on social media:Twitter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.twitter.com/middletechpod⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/middletechpod/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠h

In this episode, Logan sits down with Gaylord VanGuilder, CEO and co-founder of Buddle Skincare, an e-commerce brand set on solving diaper rash. The discussion traverses the importance of prevention in skincare, and Gaylord's extensive background in pharmaceuticals and consumer goods, including his experience with Blue Lizard Australian Sunscreen. The episode delves into the challenges of the baby skincare market, underlining the lack of R&D investment and the high costs of customer acquisition. Gaylord discusses partnerships with major retailers like Walmart, leveraging AI for business growth, and the fundraising grind for startups. Learn about Buddle's innovative approach, the impact of influencers, and insights on thriving in the competitive CPG market. Be the first to see new episodes, along with a summary, key takeaways, and upcoming events, by subscribing to Middle Tech's Spotlight Series Newsletter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://middletech.beehiiv.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Get in touch in the comments below, or re

In this episode, Logan Jones and Evan Knowles sat down with Sam Razor, the former co-founder and CEO of Hippo Manager. They discuss Sam's journey building software in the veterinary space, ultimately leading to the acquisition of the business by a private equity firm. Be the first to see new episodes, along with a summary, key takeaways, and upcoming events, by subscribing to Middle Tech's Spotlight Series Newsletter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://middletech.beehiiv.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Get in touch in the comments below, or reach out to us on social media:Twitter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.twitter.com/middletechpod⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/middletechpod/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/company/middletech/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TikTok: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.tiktok.com/@middletechpod?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/middletechpod⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Logan Jones’ SocialsX: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://x.com/lojo_ky⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.c

In this episode, Logan Jones conducts an experimental podcast featuring an AI guest named Cove, a voice from ChatGPT's advanced voice mode. The discussion covers the impressive conversational capabilities of this feature, showcasing its human-like interactions and potential applications in education, brainstorming, and content creation. Logan explores various scenarios, such as using AI for personalized learning and the possibility of integrating AI as a podcast co-host. The conversation also touches on ethical concerns, technology's rapid advancement, and the increasing demand for sustainable energy to power AI operations. Be the first to see new episodes, along with a summary, key takeaways, and upcoming events, by subscribing to Middle Tech's Spotlight Series Newsletter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://middletech.beehiiv.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Get in touch in the comments below, or reach out to us on social media:Twitter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.twitter.com/middletechpod⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com

In this episode, Logan, Evan, and TJ celebrate reaching the 300th episode of Middle Tech, diving into behind-the-scenes insights and reflecting on major developments in 2024. They share personal updates, discuss their founder-focused approach to storytelling, and explore significant trends in the tech industry, speculating on the biggest stories to watch in the future. Be the first to see new episodes, along with a summary, key takeaways, and upcoming events, by subscribing to Middle Tech's Spotlight Series Newsletter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://middletech.beehiiv.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Get in touch in the comments below, or reach out to us on social media:Twitter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.twitter.com/middletechpod⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/middletechpod/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠LinkedIn: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.linkedin.com/company/middletech/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠TikTok: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.tiktok.com/@middletechpod?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Facebook: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/middletechpod⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Logan Jones’ Social

In this episode, Evan sits down with Julia Regan discusses the inception and growth of RxLightning, a healthcare technology company focused on improving access to specialty medications. She shares her journey from identifying a significant problem in the healthcare system to launching a drug-agnostic platform that connects various stakeholders. Julia emphasizes the importance of strategic fundraising, building a flexible company culture, and leveraging networks like Endeavor to support growth. She also reflects on the challenges of scaling a startup and the critical role of hiring the right team to navigate these challenges effectively. Be the first to see new episodes, along with a summary, key takeaways, and upcoming events, by subscribing to Middle Tech's Spotlight Series Newsletter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://middletech.beehiiv.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠ Get in touch in the comments below, or reach out to us on social media:Twitter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.twitter.com/middletechpod⁠⁠⁠⁠⁠⁠⁠⁠⁠Instagram: ⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.in

In this episode, Logan Jones and Evan Knowles sit down with Travis Stanfield, co-founder and CEO of Stacklet. They discuss how Stacklet helps organizations save money and enhance security in the public cloud. Travis shares insights into the rapid growth of Stacklet, achieving their first million in revenue just seven months after launching their product. He also discusses the challenges and dynamics of running a fully remote company, timing their business inception during the COVID-19 pandemic, and the unique lifestyle of managing a tech company from a horse farm in Kentucky. Travis talks about his career journey from Microsoft to Capital One, the inspiration behind Stacklet, and the future potential of the company. Don't miss this fascinating conversation about technology, innovation, and the startup ecosystem in Kentucky. Be the first to see new episodes, along with a summary, key takeaways, and upcoming events, by subscribing to Middle Tech's Spotlight Series Newsletter: ⁠⁠⁠⁠⁠⁠⁠⁠⁠https://middletec

In this episode, Evan Knowles explores the latest developments in AI infrastructure buildout, focusing on data centers, energy consumption, and sustainability. The expansion of AI and data centers has led to supply chain issues, power challenges, and environmental concerns. NVIDIA's GPUs have become a major player in powering AI, with significant revenue growth. Countries like China and the UK are investing heavily in AI as an arms race for economic power. The power consumption of AI is unsustainable, leading to the need for innovation in data center design and energy sources. Liquid cooling and AI optimization are being explored to improve efficiency. The future of AI and energy lies in nuclear power, with fusion technology being safer and more efficient. The US needs to invest in nuclear power to stay competitive with countries like China. The AI boom will drive changes in energy and sustainability. Be the first to see new episodes, along with a summary, key takeaways, and upcoming events, by subscribin